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marketed by SUN PHARMA INCA LIFE SCIENCES
• 5TAB
₹196.33
M.R.P.: ₹206.66
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Inclusive of all taxes
Letroz tablet is an aromatase inhibitor. It blocks the conversion of androgens to estrogens by competitively binding to the haem of the cytochrome p450 subunit of the aromatase enzyme and inhibits the biosynthesis of estrogen in all the tissues. Thus inhibits the growth of breast cancer. Letroz tablet alleviates the symptoms of breast cancer such as breast lumps, bloody discharge from the nippl
Hypersensitivity to the active substance or to any of the excipients Premenopausal endocrine status Premenopausal, pregnant or lactating women .
Babies: Not applicable.
Lactating mothers: Letroz tablet is considered unsafe to use during breastfeeding.
Data suggest that the drug may cause toxicity to the baby.
Pregnancy: Letroz tablet is considered unsafe to use during pregnancy.
Studies on pregnant women and animals have shown significant harmful effects on the developing baby.
Please consult your doctor.
Driving: It is unsafe to drive while taking this medication.
It may decrease alertness, affect your vision or make you feel sleepy and dizzy.
Do not drive if these symptoms occur.
Alcohol: It is safe to consume alcohol and this tablet as it does not cause any harmful side effects.
Liver: Letroz tablets should be used with caution in patients with liver disease.
Dose adjustment of this medication is required in patients.
Please consult your doctor.
Kidney: Letroz tablet is considered safe to use in patients with kidney disease.
Dose adjustment of this medication is not required in patients.
Although, there is limited information on the use of these medicines in patients with end-stage kidney disease.
Please consult your doctor..
Fatigue Hypercholesterolemia (high cholesterol) Increased sweating Hot flashes.
Letroz tablet is an aromatase inhibitor.
It blocks the conversion of androgens to estrogens by competitively binding to the haem of the cytochrome p450 subunit of the aromatase enzyme and inhibits the biosynthesis of estrogen in all the tissues.
Thus inhibits the growth of breast cancer..
If you miss a dose, take it as soon as possible.
If it is near the time of the next dose, then skip the missed dose.
Take the prescribed dose on your regular time daily.
Don't double the dose to catch up with the missed dose..
• Letroz tablet is prescribed for the treatment of breast cancer or infertility due to anovulation • You can take the medication with or without food • Do not drive or do anything requiring concentration until you know how this medication affects you • It may cause increased sweating and hot flushes. Try to maintain cool by wearing light, and airy clothes • Cholesterol level and bone mineral density (bmd) are monitored regularly by your doctor as this medication can alter their levels • Do not take this medication if you are pregnant or breastfeeding • Inform your doctor if you are planning to have surgery or an anaesthetic • Inform your doctor if you are currently receiving or are planning to receive dental treatment.
Contraindicated • Letroz + Tamoxifen: Tamoxifen decreases levels of letroz by unspecified interaction mechanism Serious • Letroz + Ethinyl estradiol: Ethinyl estradiol decreases effects of letroz by pharmacodynamic antagonism Monitor closely • Letroz + Cholera vaccine: Letroz decreases effects of cholera vaccine by immunosuppressive effects • Letroz + Dengue vaccine: Letroz decreases effects of dengue vaccine by immunosuppressive effects • Letroz + Eluxadoline: Letroz increases levels of eluxadoline by decreasing metabolism • Letroz + Letermovir: Letermovir increases levels of letroz by affecting hepatic/intestinal enzyme cyp3a4 metabolism.
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